Detectors
Project Leader
Harrison H. Barrett, Ph.D.
Project Summary
The overall goal of Core Project I is to develop a wide variety of detector technologies, providing the flexibility needed to design imaging systems in response to specific biomedical problems under investigation in our laboratory or by our collaborators. Collaborative projects and new applications drive need for diversity of detectors, and diversity is feasible because of commonality of data acquisition and processing. Common themes include
- Accurate statistical and deterministic modeling and calibration.
- Super-listmode data acquisition, in which all available information is recorded for each event.
- Maximum-likelihood estimation of event parameters.
- Increased space-bandwidth product through larger detector area and improved spatial resolution.
- Independent detector modules for flexible system design and adaptation.
SPECT Detectors at the CGRI
Detector |
Material and Thickness |
Energy Range |
Area |
Intrinsic Resolution |
Sp-BW Product |
Depth of Interaction |
Status as of March 2008 |
|
NaI(Tl) |
30-200 keV |
10 × 10 cm2 |
~3
mm |
~1,100 |
Possible, not demonstrated |
Outmoded, still useful |
|
NaI(Tl) |
30-200 keV |
12 × 12 cm2 |
~3
mm |
~1,600 |
Possible, not demonstrated |
Routine
tool, |
3 × 3 modular camera for PET |
NaI(Tl)
or CsI(Tl) |
511 keV |
12 × 12 cm2 |
TBD |
TBD |
Demonstrated |
Improved Module Ordered |
MAPMT module |
NaI(Tl) |
30-200 keV |
5 × 5 cm2 |
<1
mm |
>2,500 |
Demonstrated |
Improved Module under test |
64 × 64 hybrid array |
CZT
or CdTe |
30-200 keV |
2.5 × 2.5 cm2 |
380 µm |
4,000 |
Demonstrated |
No current activity |
Philips Meritage clinical camera
|
NaI(Tl) |
30-200 keV |
45 × 55 cm2 |
3 mm |
27,500 |
Possible, not demonstrated |
Studies completed |
Ajat DIC-100 |
CdTe |
10-140 keV |
5 × 5 cm2 |
100 µm |
250,000 |
No |
On indefinite loan from Ajat |
Fiber-coupled scintillator, EMCCD camera(collab with RMD, Inc.) |
Columnar
CsI |
30-200 keV |
8 × 8 mm2 |
~50 µm |
|
Demonstrated |
No current activity |
Lens-coupled scintillator, Roper CCD camera |
Columnar
CsI |
|
5 × 5 cm2 |
<100 µm |
|
Possible, not demonstrated |
Used routinely, too expensive to replicate |
Bazooka-SPECT (image intensifier lens-coupled to fast, inexpensive CCD camera) |
Columnar scintillator or X-ray screen, various thicknesses
|
20-200 keV photons, betas, and positrons
|
Currently 50 mm D, 150 mm possible
|
50-100 μm
|
>~106 possible
|
Demonstrated
|
Active area of research, possible basis for FS III
|
Silicon
strip |
Crystalline
Si |
10-30 keV |
3 × 6 cm2 |
50 µm |
7 × 105 |
No |
Transferred to Vanderbilt |
Silicon
strip |
Crystalline
Si |
10-60 keV |
5 × 5 cm2 |
50 µm |
|
No |
Being tested and optimized |
Fuji
BASIS-5000 |
Photostimu-able |
10-30 keV gammas, betas |
~20 × 27.5 cm2 |
25 µm |
|
No |
In active use |
Direct Electron Imager |
P47 phosphor 3µm |
> 10 keV electrons and positrons |
Flexible |
~25µm |
106 |
No |
In active use |
Gamma-Ray Detectors
Modular scintillation cameras.
Left: Original 4-PMT camera. Right: Newer 9-PMT camera
Scintillation camera using a multi-anode PMT
Double-sided silicon strip detector and electronics
The Arizona Hybrid, a 64 × 64 CZT detector array
Illustration of 3D position estimation in the Arizona Hybrid
Detector assembly for BazookaSPECT
Simulation of 3D position estimation of 511 keV photons in anMAPMT camera with a monolithic crystal
Schematic of an electron imager based on an ultrathin phosphor
Images of a 100 nCi 90Sr/90Y beta source at different exposure times.
Images of a human breast tumor xenograft in a mouse. A. Optical image. B. Electron image with 99mTc-sestamibi at 1:1 optical magnification. C. Same, 1.7:1 magnification. D. Same, 2.7:1.
Prototype MAPMT camera in which all 64 anode signals are recorded. Shown at the right is a collimated source for camera calibration.
Home: Research Projects: Detectors
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October 2008 |