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radiology
research biographical sketches
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Eric Clarkson
Dr.
Clarkson is a Research Associate Professor in the Dept. of
Radiology and the College of Optical Sciences at The University
of Arizona. He joined The University of Arizona in 1986 as
a Research Associate in the Dept. of Radiology at the Arizona
Health Sciences Center. Dr. Clarkson received his undergraduate
degree from Rice University, Houston, TX, in 1976. He
completed his M.S. in Physics at Arizona State University,
Tempe, AZ, in 1979 and his Ph.D. in Mathematics in 1985. During
his studies at Arizona State University, he accepted a summer
instructor position from 1977-1978 at the Iranzamin International
School, Tehran, Iran, and from 1982-1984, he was an instructor
at the International School Moshi, Moshi, Tanzania. His
career continued to progress with the position of Faculty
Associate, Dept. of Mathematics, Arizona State University,
from 1985-1986. He accepted the position of Assistant
Professor, Dept. of Mathematics and Statistics, Murray State
University, Murray, KY, in 1986. Dr. Clarkson formed
a consulting company in 1992 and had the opportunity to join
Optical Technician, AXE, located in Tucson, AZ, through 1996.
Taking this private industry experience with him, Dr. Clarkson
accepted the Research Associate position, Dept. of Radiology,
at The University of Arizona in 1996 and was promoted to Research
Associate Professor, Dept. of Radiology and College of Optical
Sciences (then the Optical Sciences Center), where he continues
instructing students and pursuing his research in the areas
of theoretical and experimental framework for objective assessment
of image quality; the development and optimization of reconstruction
algorithms and imaging systems for single-photon emission
computed tomography; optimizing medical imaging systems for
estimation tasks; new algorithms for image simulation and
reconstruction and methods for evaluating and optimizing image
quality; effective methods for computing the area under the
receiver operating characteristic curve for the ideal observers
on realistic tumor detection tasks, develop new ways to compute
analytically, or approximate numerically, the statistical
properties of reconstructed medical images; elucidating the
ways in which the symmetries of an imaging system can be used
to simplify the analysis of the performance of that system
in tumor detection tasks; an analysis of the effects of constraints,
including positivity and boundedness, on reconstructions and
observer performance in tumor detection; and studying the
additional degrees of freedom in reconstruction algorithms
that result from redundant data.
William
Dallas, Ph.D.
Dr. Dallas received his PhD from the University of California
at San Diego in1973, his MS from the University of California
at San Diego in1969 and his AB from San Diego State College
in1966. His career started at the University of California
at San Diego, Applied Physics and Information Science Department
in1973. He was at the Universitaet Erlangen, Physikalisches
Institut, Germany from1973-1975, University of Washington,
Electrical Engineering Department from 1975-1976, at Virginia
Polytechnic Institute and State University, Department of
Physics from 1976-1977, at Philips GmbH Forschungslaboratorium
Hamburg, Germany from1982-1985; Scientist, 1977-1982; and
was a Visiting Scientist in 1977 at the University of Arizona,
Department of Radiology and Optical Sciences, where he is
now a Professor. His research interests include Picture
archiving and communications system, Electrical current
imaging from biomagnetic field measurements, Medical image
processing, Image display and Cardiac imaging.
Arnold
Friedman, Ph.D.
Dr. Friedman
joined the Arizona Health Sciences Center at The University
of Arizona in 2006 as Professor of Radiology. He received
his undergraduate degree from Cornell University in Chemistry
and continued his pursuit of higher education at the Albert
Einstein College of Medicine, where he received his M.D.
in 1975. Dr. Friedman completed his medical internship at
Mount Sinai Hospital, University of Connecticut, and accepted
the position of Chief Resident in Radiology at the Montefiore
Hospital in 1976. From 1979-1983, he was an Instructor
and then promoted to an Assistant Professor in the Dept.
of Radiology Uniformed Services, University of Health Sciences,
Bethesda, MD. During the same period of time, he held
the position of Assistant Professorial Lecturer in the Dept.
of Radiology, George Washington University School of Medicine,
Washington, DC, which then led to the position of Associate
Professor, George Washington University School of Medicine
through 1984. As his career continued to progress,
Dr. Friedman accepted the position of Associate Professor,
Temple University School of Medicine in Philadelphia, PA,
in 1984, and was promoted to Professor, Dept. of Diagnostic
Imaging in 1989. From 1992-1997, he held the position of
Professor and Chairman at the Medical College of Pennsylvania.
He was Associate Chairman of Radiology at Beth Israel New
York from 1997-2000 and Professor at the Albert Einstein
College of Medicine. He was Professor and Chairman of Radiology
at the University of Florida, Jacksonville from 2000-2006
before joining The University of Arizona in the fall of
2006. As a renowned research institute, The University
of Arizona will provide Dr. Friedman an environment that
will continue to support his extensive research and publications
in the areas of Abdominal Imaging, CT Colonography, Computer-Aided
Diagnosis, and 3D Imaging.
Robert
Gatenby, M.D.
Prior
to joining the University of Arizona College of Medicine
faculty in 2000, Dr. Gatenby was chairman of the Department
of Diagnostic Imaging at Fox Chase Cancer Center and Temple
University Hospital in Philadelphia, Pa. He also was a member
of the University of Arizona Department of Radiology CT/MRI
(computerized tomography/magnetic resonance imaging) section
from 1991 to 1993.
He received his
B.S.E. degree in bioengineering and mechanical sciences
from Princeton University and his medical degree from the
University of Pennsylvania in Philadelphia. He completed
an internship in internal medicine at Hershey-Penn State
Medical Center in Hershey, Pa., and a residency in diagnostic
radiology at the University of Pennsylvania.
In addition to
his clinical work, Dr. Gatenby's research interests include
mathematical modeling of tumor size and growth, including
tumor microenvironment, metabolic state and vascular supply.
He is principal
investigator for a National Institutes of Health (NIH)-funded
interdisciplinary study of acid-mediated tumor invasion,
a co-investigator for an NIH funded study of the causes
and consequences of acid pH in tumors, and a collaborator
on a recently completed study of novel radio MRI methods
for abdominal imaging.
He has had numerous
articles published in professional journals, including Nature,
Cancer Research, and Journal of Theoretical Biology. He
also is on the editorial board of Molecular Cancer Therapeutics.
Lisa
Suzanne Gobar, M.D.
After attending
Amherst College , Dr. Gobar worked in the biochemistry lab
of Dr. Eric Davidson at the California Institute of Technology.
She then graduated from Albany Medical College , moving
to Nebraska where she completed a residency in Nuclear Medicine
at the University of Nebraska . After a Fellowship in Positron
Emission Tomography, she became Medical Director of the
Center for Metabolic Imaging ( PET Center ) of Creighton
University Medical Center . At this time she was involved
in the early research on PET and Solitary Lung Nodules and
staging non-small cell lung cancer. Beginning in 1996, Dr.
Gobar became the Section Chief of Nuclear Medicine at the
University of Nebraska Medical Center, where in addition
to solo clinical coverage her responsibilities included
Director of the Residency Program in Nuclear Medicine, teaching
radiology residents, Medical Director for the CNMT Program,
and Director of the Radiation Health Center for treatment
of victims of radiation accidents. Her research focus shifted
to radiation therapy of lymphoma and other malignancies
with radioactive antibodies (e.g. Bexxar, Zevalin). Her
clinical focus was redirected to therapy with unsealed sources
with an emphasis on thyroid cancer. The Division actively
supported research efforts from other specialties, including
oncology, cardiology and gastroenterology, and collaborated
with basic scientists.
Dr. Gobar joined
the faculty at the University of Arizona in 2004. Her
research focus continues to be the imaging and treatment
of malignancies. A joint effort with Dr. Tom Miller focuses
on lymphoma, the role of PET-FDG in predicting response
to therapy and radioimmunotherapy with anti-CD20 antibodies
in follicular NHL. Another interest is the specificity
of PET-FDG imaging in the nodules of coccidioidomycosis.
The use of Y-90 glass spheres injected intratumorally
via the hepatic artery for hepatocellular cancer is being
investigated.
Selected
Publication
Elizabeth
Krupinski, Ph.D.
Dr. Krupinski
is a Research Professor at the University of Arizona in
the Departments of Radiology and Psychology where she
has been since 1992. She received her undergraduate degree
from Cornell University and PhD from Temple University,
both in Experimental Psychology. She completed her early
training in Radiology at the University of Pennsylvania.
Her main interests are in medical image perception, assessment
of observer performance, and human factors issues. She
is the Associate Director of Evaluation & Assessment
for the Arizona Telemedicine Program. She has published
extensively in these areas as they pertain to both Radiology
and Telemedicine, and has presented at conferences both
nationally and internationally. She is President of the
Medical Image Perception Society and serves on the Editorial
Boards of a number of journals in both radiology and telemedicine.
Dr. Krupinski is the North American Co-Editor of the Journal
of Telemedicine & Telecare. She serves regularly on
review panels for the NIH, DoD, FDA and TATRC. She is
currently the Vice President of the ATA.
Zhonglin
Liu, Ph.D.
Dr. Liu received
his medical degree from the China Medical University,
China in 1984 and continued his education at the China
Medical University in pursuit of an MS degree in Medical
Imaging, which was awarded to him in 1991. He
began his career as a Medical Resident in 1984 at the
Second University Hospital, China Medical University,
China, and Assistant Professor, Dept. of Nuclear Medicine
in 1991. Dr. Liu accepted a position as a Postdoctoral
Research Associate in the Dept. of Nuclear Cardiology
at the University of Oklahoma, Norman, OK, from 1995-2000.
The University of Arizona, Tucson, AZ, extended an offer
of Research Assistant Professor to Dr. Liu in 2000 to
join the group of researchers in the Center for Gamma-Ray
Imaging, funded by the National Institutes of Health.
This opportunity allowed him to pursue his research
in Nuclear Cardiology Imaging. Dr. Liu was promoted
to Research Associate Professor in 2005 and has made
considerable contributions to his research in publications
and data collection. He was the winner of the Journal
of Nuclear Medicine’s 2nd Paper Award for Basic
Science Investigations, Society of Nuclear Medicine.
Terry
O. Matsunaga,
PharmD,
PhD
Dr.
Terry Matsunaga comes to us after 16 years in the industry
where he worked along side Dr. Evan Unger at ImaRx
Pharmaceutical Corp. to invent and develop the lipid-coated
microbubble product now being sold under the brand
name Definity®.
In addition,
over the past five years, Dr. Matsunaga focused his
attention upon the use of ultrasound-mediated bubble
cavitation for dispersion of vascular thrombi. He was
appointed to a position as Research Professor of Radiology
in September, 2007.
Dr. Matsunaga received his AB degree
in Biochemistry from the University of California at
Berkeley, followed by a Pharm.D. in Clinical Pharmacy
at the University of California San Francisco (UCSF).
Following a year of clinical training as a Resident
at the University of Michigan, Terry returned to UCSF
where he received his Ph.D. in Pharmaceutical Chemistry.
From 1986 through 1992, he was a NIDA post-doctoral
fellow in the laboratory of Professor Victor J. Hruby
in the Dept. of Chemistry at the University of Arizona.
His research interests lie in the area of ultrasound
contrast agents and novel drug delivery systems for
drug and gene delivery. Dr. Matsunaga regularly sits
on grant review study sections for various programs
in the NIH (i.e. NIDA, RAID, SBIR, and STTR) and the
Department of Defense (Breast Cancer and Prostate Cancer
programs).
Hans
Roehrig, Ph.D.
Dr. Roehrig received his MS and PhD from the Justus
Liebig University, Giessen, Germany in 1961 and 1964
respectively. He started his career at the Farbenfabriken
Bayer, Leverkusen, Germany from 1965-1966, moved to
the U.S. Army Night Vision Laboratory, Physicist from
1967-1972, was at the University of Rhode Island, Research
Associate from 1972-1973 and has been at the University
of Arizona: Department of Radiology and Optical Sciences
since 1973. He is currently a Research Professor Emeritus.
He became an SPIE, Fellow in1990 and won the Association
of University Radiologists, Herbert M. Stauffer Award
in1997. His research interests include development of
the totally digital radiology department, Physical evaluation
of photoelectronic imaging devices, Physical evaluation
of medical imaging devices
Research, and Application of photoelectronic imaging
devices to diagnostic radiology.
Gail
Stevenson, Ph.D.
Dr. Stevenson
studied Animal Science at The University of Arizona
and received her BS degree in 1974. After completing
her BS, she attended Colorado State University, Ft.
Collins, CO, and received her DVM in 1979. She had an
opportunity as a Research Assistant to teach and perform
research on several projects prior to continuing her
education toward a DVM degree. After completion
of her DVM degree, Dr. Stevenson returned to Tucson,
AZ, and worked as a veterinarian for several years.
Her interests remained focused on research, and she
was presented with an opportunity in 1984 to work in
research at The University of Arizona in the Dept. of
Anatomy as a Research Assistant. Dr. Stevenson continues
to pursue her research opportunities at The University
of Arizona and has worked in several departments, including
Anatomy, Neural Systems, and Radiology. Currently, she
holds the position of Research Assistant Professor,
Center for Gamma-Ray Imaging, a National Institutes
of Health-funded Research Center, in the Dept. of Radiology.
Her research continues to expand in the areas of nuclear
imaging, behavior studies, data collection, and publications.
Russell
S. Witte, Ph.D.
Russell Witte received his B.S. degree with
Honors from the University of Arizona in 1993. After
extensive travel to Europe and Brazil, he returned to
the United States for graduate school in Bioengineering
at Arizona State University and embarked on a research
project using chronic microelectrode arrays to describe
sensory coding and cortical plasticity in the mammalian
brain. After earning his Ph.D. in Bioengineering in
2002, Dr. Witte moved to University of Michigan in Ann
Arbor to develop new ultrasound contrast mechanisms
for imaging especially excitable tissue (i.e., brain,
nerve and muscle). As a member of the Biomedical Ultrasonics
Laboratory, he helped devise several new imaging techniques,
such as ultrasound current source density imaging for
detecting current flow in biological tissue. In July
2007, Dr. Witte became Assistant Professor of Radiology
at the University of Arizona. As Director of the Experimental
Ultrasound and Neural Imaging Laboratory, he continues
to develop new imaging methods using a combination of
light, ultrasound and radiofrequency that potentially
impact a variety of medical disorders from epilepsy
to cancer.
James
M. Woolfenden, M.D.
Dr. Woolfenden
has been a leader of the medical staff of UMC. He has
chaired numerous committees and has served as chief
of staff. Recently he concluded 12 years of service
as a member of the Board of Directors of University
Medical Center Corporation. Dr. Woofenden
has been active in numerous professional organizations,
including: Chairman,
American Board of Nuclear Medicine
President, American College of Nuclear Physicians
Chairman, Diagnostic Radiology Study Section, National
Institutes of Health
Board Member, Society of Nuclear MedicineDr. Woolfenden
is currently: Associate
Director, Center for Gamma-Ray Imaging, University of
Arizona, funded by National Institutes of Health
Full Investigator, Arizona Cancer Center
Senior Clinical Scientist, Sarver Heart Center
His research
interests include high-resolution imaging and treatment
of cancer using radioactive isotopes.
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